MODUL 1- Basic Research Approaches

The Molecular Pathways Driving Host-Pathogen Interactions – Attack & Defense

Objective 1-1: Use of cultured primary innate immune cells to identify the network of genes and signaling pathways determining virulence of fungal pathogens in vitro

Objective 1-2: Use of animal mouse models and knock-out mice cells to establish the role of host signaling pathways in pathogen defence

Objective 1-3: Study of stress signaling and its interplay through the major MAP kinases ERK and p38, and their role in modulating adaptive versus protective responses